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 The San Francisco Bay Area Mass Spectrometry (BAMS) discussion group





 Tuesday, February 2nd, 2010 6:00 pm to 9:30 pm

Location:
Crowne Plaza Hotel
Foster City, CA


Dinner reservations required by 6:00 PM on Thursday, January 28th, 2010




**** N. Leigh Anderson, Ph.D. Founder and CEO of the Plasma Proteome Institute, Washington D.C. ****
 
Title: "Roles of Mass Spectrometry in Expanding the Clinical Plasma Proteome"
 
ABSTRACT:

The current clinical plasma proteome consists of 109 proteins measured by FDA-cleared or approved assays and 96 proteins measured using widely-available laboratory developed tests, in total about 1% of the baseline human proteome. However the rate at which new protein analytes achieve FDA approval has remained essentially constant over the past 15 years at 1.5 proteins per year, insufficient to meet clear medical needs. The striking shortfall in new protein diagnostics emerging from proteomics research reflects a lack of critical biomarker verification capacity. In order to bridge the gap between biomarker discovery and clinical use, a new approach to verification is proposed: multiplexed panels of specific candidate assays based on hybrid immuno-mass spectrometric (SISCAPA) detection. By combining high sensitivity, high throughput, and precision with use of small plasma samples, a platform for systematic verification of hundreds of candidates in thousands of samples can be implemented. Such systematic studies will finally allow us to test the “strong biomarker hypothesis”: that molecular biomarkers exist for all major disease states. An extension of this approach, the hPDQ project providing a library of specific tests for all 21,300 human proteins, could provide the larger biomedical research community with direct quantitative access to the entire human proteome.

SPEAKER BIOGRAPHY:

Dr. Anderson obtained his B.A. in Physics with honors from Yale and a Ph.D. in Molecular Biology from Cambridge University (England) where he worked with M. F. Perutz as a Churchill Fellow at the MRC Laboratory of Molecular Biology. Subsequently he founded (with Dr. Norman Anderson) the Molecular Anatomy Program at the Argonne National Laboratory (Chicago) where his work in the development of 2-D electrophoresis and molecular database technology earned him, among other distinctions, the 1983 Pittsburgh Analytical Chemistry Award. Prior to founding PPI, Dr. Anderson was Chief Scientific Officer at Large Scale Biology Corporation, whose proteomics division he founded in 1985, and co-led a successful IPO based largely on the proteomics technology platform (working with J.P. Morgan, Chase H&Q and Wm Blair).


More recently Dr. Anderson has developed novel technologies for quantitation of protein biomarkers using mass spectrometry, receiving the 2009 HUPO Distinguished Achievement Award in Proteomic Science. Dr. Anderson has published more than 150 scientific papers, one book and 32 patents. Dr. Anderson currently serves as a Principal of Anderson Forschung Group LLC, the Board of Directors of Luna Innovations (a developer of novel materials and sensors) and on numerous scientific advisory boards.


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If you would like to become a sponsor and have not done so, please contact Ahmed Elbaggari or Maryann Shen. BAMS corporate sponsors for 2010 will have a place to put up a technical poster and a table to distribute literature or demonstrate products during the Annual BAMS Vendor Night.
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We look forward to seeing you at the next meeting!
 
Respectfully, we remain your servants,

Your BAMS Executive Team.






PS-If you would like your country of Birth be shown here, send me an e-mail..... Webmaster.
Meeting details
Date: Tuesday  February 2nd, 2010
Time: 6:00 pm Social hour, registration (no-host cocktails)

7:00 pm Dinner

8:00 pm Presentation
Dinner:  
featuring:    
Dinner selections are:

A) Flank Steak- Anise Marinade

 B) Grilled Salmon- Champagne Buerre Blanc, Herb Roasted Veggies and Rice Pilaf.

C) Mediterranian Farfalle Pasta with Sun Dried Tomatoes, Olives, Basil, Mushrooms(Vegetraian)






Cost:
$40
BAMS members*

$50
Non-members

$70
BAMS membership plus dinner cost

$20
Students only

$300
2009 Corporate Sponsors


Dinner reservations required by 6:00 PM, Thursday the 28th of January, 2010

*Note:  BAMS memberships are for the calendar year and should be renewed with the first event you attend in 2010.  Dues ($30.00) may be paid while registering for dinner.  If you are unsure of your Membership status, please email Ahmed Elbaggari.

Crowne Plaza Hotel
1221 Chess Drive
Foster City, CA 94404 

Google Map to Crowne Plasa Hotel
Hotel Phone: 1-800-972-3124  


 

Did you see or hear about the BAMS talk by Professor Murayama entitled "What is Mass?"  What is it we are measuring after all?  Check it out!  Go to ctp.berkeley.edu and click on "Popular Talks & Articles" for a QuickTime file.


As a service to our members, we post Employment postings (No new postings since November, 2009).
but they have been slim.
California Analytical Chemists Organization (CACO- used to be called Bay Area Analytical Chemists (BAAC)) has some Great Position listings. Click here for the ASP (active server pages) CACO JOB LISTINGS.

The San Francisco Bay Area Mass Spectrometry discussion group was formed in 1980 to provide a regular gathering for people interested in mass spectrometry and allied topics. BAMS currently has a membership of about 270 individual and 20 corporate members, and meets 7-10 times per year for a midweek dinner and lecture.  Meetings attract between 30 and 90 people, and are held at a restaurant or hotel in the bay area convenient for our speaker.  We usually convene at 6:00 pm for cocktails, dinner at 6:30 to 7:00 pm, and lecture at 7:30 to 8:00 pm.

If you have suggestions for a meeting topic, or know of a prominent mass spectrometrist who will be visiting the bay area, please contact our Program Chair, Maryann Shen.

To become a member, please fill out and mail to BAMS the membership form with BAMS ADDRESS HERE.
BAMS has been fortunate to have had many excellent speakers in our history.
If you have suggestions for a meeting topic please contact our program chair Maryann Shen.
If you have questions or comments about BAMS, please contact one of the Current BAMS Officers.
Please thank our Corporate Sponsors who help keep BAMS membership and dinner costs low.
Here are some internet links that may be of interest to BAMS members.

Here is a link to The RAS Memorial Fund did provide four $750 travel awards for 2009...unknown if they are doing the same for 2010.   Richard A. Schaeffer Memorial Fund.  Deadline to apply was 9 of February, 2009. Even though the dealine has past for 2009, they do offer other awards. E-mail contact to Joseph J. Grabowski   Associate Professor, Department of Chemistry Director of Undergraduate Research, Arts & Sciences University of Pittsburgh, PA.
Contact the Webmaster directly if you desire the application in PDF format.
 

If you have comments or suggestions for this web site, please email Arthur Henrick, BAMS Webmaster starting in 2009 BAMS.Webmaster@gmail.com



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